Best Hybrid Nursing Programs - RN to BSN, ADN, MSN, CRNA

Hybrid nursing programs offer the flexibility of online learning with the essential hands-on training required in healthcare. From entry-level licensed practical nurse (LPN) tracks to advanced certified registered nurse anesthetist (CRNA) pathways, hybrid degree programs cater to a wide range of nursing students and career stages.

These options are ideal for students balancing work, family, or geographic limitations. Some of the best regionally accredited nursing programs across the U.S. are highlighted below. Keep reading to discover which schools offer the flexibility and rigor you need.

What Is a Hybrid Nursing Program?

A hybrid nursing program combines online coursework with in-person clinical training, offering flexibility without sacrificing hands-on experience. Hybrid accelerated nursing programs allow students to complete their degrees more quickly by blending digital convenience with essential on-site practice, which is ideal for working nurses or those seeking a faster route to advanced credentials.

Types of Hybrid Nursing Programs

Hybrid nursing programs come in various formats, offering flexible pathways for different education levels, career goals, and nursing specialties.

• Hybrid Associate Degree in Nursing (ADN) programs: Hybrid ADN programs combine online nursing coursework with in-person clinical training, allowing prospective students to earn an entry-level nursing degree with greater flexibility. These online nursing degree programs are ideal for those beginning their journey toward becoming a registered nurse (RN).
• Hybrid RN to BSN programs: Designed for licensed RNs seeking to advance their careers, hybrid RN to BSN programs offer a streamlined path to a bachelor's degree. Students complete most nursing courses online, with occasional in-person components for labs or patient care assessments.
• Hybrid Accelerated Bachelor of Science in Nursing (ABSN) programs: ABSN programs are fast-track options for those who hold a non-nursing baccalaureate degree. These hybrid nursing programs for non-nurses blend online instruction with clinical experiences, helping career changers gain the critical thinking skills necessary to transition into nursing in as little as 12 to 18 months.
• Hybrid Master of Science in Nursing (MSN) programs: Hybrid MSN programs cater to working nurses aiming for leadership, education, or advanced clinical roles in the health sciences. These programs combine online courses with on-site nursing care, offering specialization tracks such as nurse educator, nurse practitioner, or nursing administrator.
• Hybrid Licensed Practical Nurse (LPN) programs: Hybrid LPN programs are suitable for those looking to enter the field quickly. These online nursing programs typically include self-paced theory modules with required clinical hours completed at approved healthcare facilities and convenient start dates.
• Hybrid Certified Registered Nurse Anesthetist (CRNA) Programs: These advanced programs prepare RNs for highly specialized anesthesia roles. Hybrid CRNA programs often deliver didactic coursework online while requiring intensive, hands-on clinical residencies and simulation labs at partnering institutions.

Best Hybrid Nursing Programs by Category

Explore top-rated hybrid nursing programs in each category, from LPN to CRNA, designed to fit diverse schedules and career paths while offering competitive learning experiences.

Best Hybrid ADN Programs

These three standout schools offer exceptional flexibility, clinical excellence, and strong licensure outcomes. Each program blends online theory with in-person labs and clinical rotations to prepare students for success as registered nurses.

Rasmussen University

Program name: Professional Nursing Associate's Degree in Nursing (ADN/RN)

Program Type: Hybrid (online and on-campus)

Program duration: 21 months or 18 months via LPN-to-RN bridge

Overview: This hybrid ADN program blends online coursework with on-campus lab simulations and in-person clinical rotations, preparing students for the National Council Licensure Examination for Registered Nurses (NCLEX-RN) and a fulfilling career in the healthcare field.

Columbus State Community College

Program name: Registered Nurse (RN) Associate Degree in Nursing - Blended Program

Program Type: Hybrid (blended online and on-campus)

Program duration: Two years

Overview: The blended ADN program delivers theory entirely online with required on-campus labs and clinical rotations for one or two days each week in central Ohio. Advanced standing options that prove competency in the field allow LPNs, paramedics, or military medics to complete the requirements more quickly with prior learning credit hours.

John A. Logan College

Program name: Nursing ADN Hybrid Online Full-Time AAS Degree

Program Type: Hybrid (online and on-campus)

Program duration: 15 months

Overview: This hybrid ADN program delivers theory online while requiring weekly on-campus lab sessions and face-to-face clinical rotations in local facilities for full-time students prepared for RN licensure. Classes include advanced pharmacology, pediatric nursing, and mental health classes.

Learn More: Best 2-Year Nursing Programs

Best Hybrid RN to BSN Programs

These outstanding hybrid RN to BSN degree programs offer licensed RNs the opportunity to earn a bachelor's degree with flexibility, combining online coursework with essential in-person clinical or lab requirements.

South Florida College of Nursing

Program name: Bachelor of Science in Nursing (RN to BSN) Online-Hybrid Program

Program Type: Hybrid (online and on-campus)

Program duration: 12 to 18 months

Overview: This RN to BSN program delivers most coursework online, with select on-campus sessions for labs and hands-on learning, allowing licensed RNs to complete their BSN with flexibility and support.

University of Texas at Arlington

Program name: Registered Nurse to Bachelor of Science in Nursing Online

Program Type: Hybrid (online and on-campus)

Program duration: Nine to 15 months

Overview: This RN to BSN program builds on your existing RN status, allowing most coursework to be completed online with application-based projects performed in your workplace instead of on-campus labs. As one of the fastest RN to BSN programs online, it's designed for working nurses seeking a flexible path to their BSN.

University of Florida

Program name: Bachelor of Science in Nursing (RN to BSN)

Program Type: Hybrid (online and on-campus)

Program duration: 15 months

Overview: This CCNE-accredited RN to BSN program delivers all coursework online and includes 90 clinical hours via virtual simulation and independent community-based projects, tailored for working RNs seeking advancement.

Read More: Self-Paced RN to BSN Programs

Best Hybrid ABSN Programs

Hybrid ABSN programs offer a fast-track route for students with non-nursing degrees to enter the nursing field. These programs blend online learning with in-person clinical training, making them ideal for those seeking a flexible, intensive option. Some schools also offer a part-time nursing school program structure, helping students balance academics with personal or professional obligations.

Holy Family University

Program name: Second Degree Distance Hybrid Bachelor of Science in Nursing (BSN)

Program Type: Accelerated hybrid (online and on-campus)

Program duration: 14 months

Overview:This hybrid ABSN is designed for students who already hold a bachelor's degree, featuring 100% online coursework, a single one-week residency on campus, and local clinical placements. It's perfect for an efficient entry into nursing.

Baylor University

Program name: Distance Accelerated Bachelor of Science in Nursing

Program Type: Accelerated hybrid (online and on-campus)

Program duration: 12 months

Overview: Designed for individuals with a prior bachelor's degree in a non-nursing field, this CCNE-accredited accelerated BSN online program delivers 100% of coursework online, includes two in-person skill lab residencies in Dallas, and features in-state clinical rotations � completing most nursing requirements in one year.

Learn More: 1-Year ABSN Programs Online

Best Hybrid MSN Programs

Hybrid MSN programs offer advanced education for registered nurses seeking roles in leadership, education, or advanced clinical practice. These programs combine flexible online coursework with essential in-person components, such as labs or clinical practicums. Below are top schools offering hybrid MSN options tailored to working professionals.

Duke University School of Nursing

Program name: Master of Science in Nursing (MSN)

Program Type: Hybrid (online and on-campus)

Program duration: Approximately two years

Overview: Duke's CCNE-accredited MSN offers a blend of flexible, online core courses and immersive on-campus experiences, paired with local or regional clinical placements. It is available in eight clinical APRN majors and three nonclinical systems majors.

Emory and Henry University

Program name: Master of Science in Nursing (MSN)

Program Type: Hybrid (online and on-campus)

Program duration: 18 months

Overview: This accredited MSN program offers two tracks: Family Nurse Practitioner (FNP) and Clinical Nurse Specialist/Nurse Educator. It is delivered primarily online, with on-campus intensives and hands-on clinical practicum placements. An accelerated option is available for ADN-to-MSN students.

Vanderbilt University School of Nursing

Program name: Master of Science in Nursing (MSN)

Program Type: Hybrid (online and on-campus)

Program duration: 16 months

Overview: Ideal for working RNs seeking flexibility, this program offers advanced practice specialties through mostly online coursework. It is complemented by short, immersive on-campus sessions and local clinical placements.

Best Hybrid LPN Programs

Hybrid LPN programs provide a flexible learning option for those pursuing entry-level nursing careers. Often referred to as licensed vocational nurse (LVN) programs in states like Texas and California, they blend online coursework with in-person clinical requirements. Many of the schools featured below offer accelerated online LPN programs, allowing students to complete their training faster while still meeting licensure and hands-on experience requirements.

Lake Area Technical College

Program name: Licensed Practical Nursing Hybrid E-Degree

Program Type: Hybrid (online and on-campus)

Program duration: 11 months full-time or 18 months part-time

Overview: LATC offers a flexible LPN program blending online lectures with intensive in-person clinical and simulation experiences. This degree is ideal for students balancing obligations yet aiming to earn their LPN quickly and efficiently.

North Central Texas College

Program name: Vocational Nursing (LVN) Program - Online Hybrid

Program Type: Hybrid (online and on-campus)

Program duration: 12 months

Overview: NCTC's hybrid LVN program allows students to complete theory coursework online while attending scheduled on-campus lab sessions and hands-on clinical rotations. This program stands out as one of only two hybrid LVN programs in Texas approved by the Texas Board of Nursing.

Tennessee College of Applied Technology

Program name: Hybrid Practical Nursing

Program Type: Hybrid (online and on-campus)

Program duration: 12 months

Overview: Combining roughly equal parts in-person and online learning, this hybrid LVN program in Tennessee blends hands-on skill days with virtual classroom sessions. Graduates of the hybrid program complete the same curriculum as the traditional track and earn eligibility to sit for the NCLEX-PN.

Learn More: Fastest LPN Programs Online

Best Hybrid CRNA Programs

Hybrid CRNA programs offer a flexible pathway for experienced registered nurses to pursue one of the most advanced and highly specialized roles in nursing. These programs typically combine rigorous online coursework with periodic on-campus immersions and extensive in-person clinical residencies. Below, we highlight top hybrid CRNA programs that allow working professionals to advance their education while meeting the intensive training requirements of nurse anesthesia practice.

University of Arizona College of Nursing

Program name: Doctor of Nursing Practice (DNP) Nurse Anesthesiology Specialty

Program Type: Hybrid (online and on-campus)

Program duration: Three years

Overview: Blending advanced online instruction with hands-on learning, this DNP prepares experienced ICU RNs for CRNA practice through intensive simulation labs, immersive on-campus sessions, and extensive regional clinical placements � complete with accreditation from both the CCNE and COA.

Virginia Commonwealth University

Program name: Doctor of Nurse Anesthesia Practice (DNAP)

Program Type: Hybrid (online and on-campus)

Program duration: Three years

Overview: This BSN-to-DNAP pathway begins with a hybrid schedule, offering early coursework through synchronous video links and local site instruction. It then transitions into immersive on-campus clinical training. Designed to support students, it delivers the full nurse anesthesia curriculum across VCU's Richmond and regional sites.

Wake Forest University School of Medicine

Program name: Doctor of Nursing Practice (DNP) with Nurse Anesthesia Specialization

Program Type: Hybrid (online and on-campus)

Program duration: Three years

Overview: The program integrates online didactic instruction with immersive in-person simulation training and extensive clinical practicum experiences. Following over 2,500 hours across approximately 800 anesthesia cases, graduates are fully prepared for CRNA practice in diverse clinical settings.

Learn More: CRNA Schools With High Acceptance Rates

Explore Online Nursing Degrees

Explore more flexible, career-focused healthcare degrees by browsing additional hybrid program options available at Learn.org. LEarn mroe about these programs and your scholarship opportunities to help pay for them. Reach out to schools directly to find out more about admissions and financial aid.